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KMID : 0357319950300010045
Journal of the Korean Society for Microbiology
1995 Volume.30 No. 1 p.45 ~ p.55
Morphological Changes of Bacteria by Skin Disinfectants
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Abstract
Disinfection is a method by which the resident flora of the pathogenic organisms are removed or killed. In this study, a comparative test was conducted to evaluate the bactericidal activities of 6 kinds of hospital hand disinfectants by using
AOAC
and
BSI Chick-Martin methods. Antimicrobial activities of each disinfectant were specific to each test organism in both AOAC and BSI Chick-Martin method. In the observation of chemical disinfection activities by scanning eletron microscopy, B.
subtilis
treated with benzalkonium chloride underwent a characteristic morphological change in bacilli to round forms. However, the same organisms treated with the other disinfectants were showed to be less sensitive to morphological changes in the
diluent
solutions and showed a large number of substrates attached to their cell surface. The other test microorganisms treated with benzalkonium chloride made characteristic morphological change of bacilli to round forms, and showed a large number of
substrates attached to their cell surface. But Staphlococcus aureus developed into a large form in size.
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